Like in all dogs, genetic diseases occur in Kooikerhondjes. When choosing breeding pairs, it is recommended to avoid inbreeding as much as possible if one of the known genetic diseases of the breed is seen in earlier generations of family members.
Despite careful breeding, by the breeding rules and with the extensive information of the ‘Club register’, genetic diseases cannot entirely be prevented.
Down here follows a list of the hereditary diseases that can appear in the Kooikerhondje.
A coagulation abnormality that causes bleeding (wounds, heat cycle) to last longer and to be life threatening.
In the Kooikerhondje, type 3 of this bleeding disorder is found (total absence of vWFactor). Often, gastrointestinal bleeding and urogenital bleeding occur.
Because DNA analysis is available since 1990, we nowadays hardly see affected animals within the VHNK population.
The VHNK offers funding for members and non-members for VWD testing at Utrecht University (obligatory for all breeding animals).
In this disorder, the patella (kneecap) is able to move out of its normal location (manually or spontaneously).
The Kooikerhondje breed is generally known with medial patella luxation, but in some cases the luxation is lateral. Severe forms (PL grade 2 and higher) cause instant lameness in the dog. Often they cry out of pain. The leg can not be used anymore. If the kneecap spontaneously moves back to its location, the dog will immediately be able to walk again.
15% of the tested dogs are mild cases (up to grade 1). About one time a year a severe case (grade 2 and more) is reported to the VHNK.
The breeding policy (obligatory testing of all breeding animals / using a minimum of affected animals) makes sure the frequency of affected animals is kept at a low level.
Also known as ‘Kooikerverlamming’ (Kooiker paralysis)
Neurological disorder that affects the spinal cord white matter and leads to paralysis.
Affected dogs show symptoms from the age of 6 to 15 months. At first, the symptoms are mild: subtle coordination problems in the hind limbs. As the disorder advances, the progressive character will be emphasized. The dogs will ‘walk like a drunk’ in the rear end. At this time, the front will also show functioning problems and dogs show a loss of postural reflexes.
A restrictive breeding policy and proper registration made sure that over the past few years this disease has been reported less than once a year.
Affected animals are not in pain, but the disease is progressive and leads to the death of the dog before it has reached the age of 2. The diagnosis can only be confirmed by dissection and pathological research of the thoracic and cervical spinal cord. The VHNK funds this research. In order to develop a DNA test, the VHNK is collecting samples of affected animals.
Epilepsy is a disorder that causes dogs to have recurring seizures. Depending on the type of epilepsy, seizures can be described as recurring abnormal behaviour with a number of distinctive characteristics.
Epilepsy falls into two categories: primary epilepsy and secondary epilepsy. Primary epilepsy is the hereditary form.
In the veterinary world the definition of epilepsy requires that seizures, in any form, are recurrent.
Seizures can vary from small, atypical seizures, showing a broad variety of symptoms, to classic generalised seizures. Classic seizures generally occur within the age of 6 months to 5 years (not strictly!).
Seizures often happen at night or in early morning. The dog is unconscious and will fall on its side, has extended legs and moves its head over its back to the rear. After that, the dog will paddle with all four limbs. The seizure lasts between a couple of seconds and a couple of minutes. Sometimes a seizure can be predicted, most of the time it can’t.
The next stage is called the post-ictal period. This recovery can come in many forms and takes seconds to hours. Atypical seizures can limit themselves to abnormal muscular movement of paws or eyelids etc. and the dog is generally more conscious.
Because of the special attention the VHNK is paying to this disorder, the number of affected dogs reported is declining. In recent years the number varied between 1 and 5 dogs a year.
If a dog has over one seizure a month, it is recommended to start treatment. The usual medication prescribed is Phenobarbital. The response varies per dog. For more information we refer to a veterinarian or veterinary specialist in neurology.
The Information committee is willing to help finding more information or making contact with a veterinary specialist.
Autoimmune disease that causes chronic inflammation of one or more muscles, preventing them to function, which results in muscle weakness of the affected muscles. Myositis is a progressive disease with a very poor prognosis.
There are two groups. A group of relatively young dogs with mainly swallowing or eating problems. The second group of dogs is young to middle aged and has musculoskeletal problems or a combination with swallowing problems.
Depending on the location and kind of myositis, the most common symptoms are:
- Reduced endurance
- Muscle weakness
- Swallowing problems
- (Muscular) pain!
- Total exhaustion, no more desire to play / walk.
- Limping / stiffness
- Walking with curved back
- Anorexia / not wanting to eat
Because many symptoms are also indications of other diseases and often start as “vague complaints”, myositis will often be difficult to recognize / distinguish. To make a definitive diagnosis, additional blood tests to muscle values, a muscle biopsy supplemented by EMG and in case of swallowing problems a bronchoscopy by a veterinary specialist, are required.
Unfortunately we see polymyositis more regularly at the moment. The frequency is around 1% of the population.
Treatment with medication is not always successful and the dog will die. At this moment research is done to the (genetic) cause and variation of the disease in the kooiker breed. It’s possible to submit material for autopsy for the purpose of the research project. For more information, please refer to Dr. P. Mandigers, working as a veterinary specialist in VSC ‘De Wagenrenk’ and at Utrecht University firstname.lastname@example.org, or contact the Information Committee of the VHNK.
August 2018 – How researcher and owner can help eachother. Read here: Polymyositis in Het Nederlandse Kooikerhondje
April 2019 – Some important steps forward in the research around polymyositis: Notification polymyositis
Within the Kooikerhondje population are only a few hereditary eye diseases, for instance:
Non congenital cataract, clouding of the lens inside the eye that can lead to blindness.
Because of restrictive breeding, the disorder is rarely seen in the breed.
An extra set of eyelashes, can be corrected surgically with a good prognosis.
A strict breeding policy makes sure that there are very few dogs with eye problems within the breed.